In men malar pattern is more common than the centrofacial and mandibular patterns. Similarly, our patients also had centrofacial pattern in 48. A clinicoepidemiological study of 312 cases melasma is an acquired increased pigmentation of the skin, characterized by graybrown symmetrical patches, mostly in. Doubleblind, placebocontrolled trial to evaluate the. A clinicoepidemiological study of melasma in pune patients hilaris. Melasma is a common skin pigmentation issue that causes dark, blotchy, and uneven skin tone on sunexposed areas, chiefly on the face. Melasma is an acquired chronic hypermelanosis of sunexposed areas which significantly impacts quality of life. Melasma improving spontaneously upon switching from a. Melasma is a common, acquired, hyperpigmentary condition of the face characterised by symmetrical and asymptomatic brownish or brownish black macules and patches involving sunexposed areas. The hospital caters to patients from all sections of the society. Sir, i read with much interest the article melasma.
A few cases of melasma on the neck and forearms have also been reported in men. The many clinicopathologic faces of actinic keratosis. Clinicoepidemiological study of patients with melasma in. The primary efficacy variable was the reduction in mmasi score between the baseline and the end of the study. Although the general accepted female to male ratio is 9. Moreover, it was reported to have a significant impact on quality of life. A clinical, epidemiological, and etiological study s kumar, bb mahajan, nidhi kamra department of skin and vd, guru gobind singh medical college and. While the problem can be embarrassing, the appearance of dark patches of skin does not. Thus, this study is undertaken to study the clinicoepidemiological pattern, dermascopy, woods lamp findings and the quality of life in patients with melasma. Among the 80 female patients, 23 reported onset of melasma during pregnancy. Ortonne jp, arellano i, berneburg m, cestari t, chan h, grimes p, et al. Clinicoepidemiological study of melasma in men charupalli k.
Melasma is almost invariably a clinical diagnosis and does not require any type of skin biopsy or laboratory workup. The average age of onset of melasma among indians was found to be 33. There are few epidemiological studies in medical literature concerning the disease, even less in the nepalese population. A comparative study between two topical treatments. Melasma is a common pigmentation disorder among indians. Men comprised only 18% in our study as compared to 10% of all cases in a previous study. Melasma had a peak incidence of onset in the third decade with mean age of onset at 31. Melasma occurs due to an increased melanogenesis in the melanocytes. Melasma is a common acquired hypermelanosis of the skin that has been associated with several etiologic factors including ultraviolet light exposure, pregnancy, and oral contraceptives ocps 1. Pdf a clinicoepidemiological study of melasma researchgate. This is an area which has a rather sparse representation, particularly in the indian literature, despite melasma being a very common disorder in this part of the world. Acquired facial melanosis is a common presentation in indian patients, causing cosmetic disfigurement with considerable psychosocial impact. The clinical pattern of presentation classified the cases of melasma into centrofacial, malar and mandibular types. On dermatoscopic examination, 58% cases had epidermal melasma, 23% had dermal melasma and 19% had mixed melasma.
Females comprised the majority of cases seen in 29 out of 36 cases and the common age group affected was in late third decade. If the diagnosis is in question, ruling out other conditions based on the patients history and physical examination should be the initial approach. A clinicoepidemiological study of facial melanosis hassan. A crosssectional, multicentric clinicoepidemiological. Clinical patterns and epidemiological characteristics of.
Medical college, university of kashmir, srinagar, jammu and kashmir, india. In this prospective, randomized, doubleblind, placebocontrolled study, we evaluated the efficacy of oral ple as an adjunctive treatment for melasma in this population. Fortyone percent of women surveyed in one study had onset of melasma after pregnancy, and 25% after starting an ocp 2. A clinicoepidemiological study of melasma in pune patients.
Our present research aims to study the clinicoepidemiological pattern and the precipitating or. It takes into account an areaweighted pigmentation score and pigment homogeneity across the cheeks, chin, and forehead. The present study aimed to investigate the epidemiology of melasma in nepalese patients and to focus on the clinical manifestations and factors. A clinical study of melasma and assessment of dermatology. A total of 36 patients were enrolled for the study over a period of three months. In none of these studies, melasma patients were assessed clinically by psychiatrist for diagnosis of various psychiatric disorders, which is the strength of this study. Clinical patterns and epidemiological characteristics of melasma in. Clinicoepidemiological study of patients with melasma in a tertiary. Dermatoscope helps in diagnosis and prognosis of melasma. Melasma is an acquired, chronic, and symmetrical hypermelanosis, characterized by brown patches of variable darkness on sun exposed areas of body. However, the study does not cite cases of mixed melasma. Though clinicoepidemiological profile of melasma in india has been extensively studied, there is paucity of data on effect on quality of life. This is an area which has a rather sparse representation, particularly in the indian literature, despite melasma being a.
At each visit, the study team member assessed the area of involvement and level of darkness at the forehead, right and left malar regions, and the chin. An indian study of 312 patients with melasma found a 4. A clinicodermatoscopic study of 100 cases of melasma in a. Nearly 35% of the study population gave a defi nite exacerbation due to sun exposure.
Diagnosis in case of suspected betalactam antibiotic. The exact prevalence of melasma is unknown in most of. Studies have shown that melasma has a female predominance 6, 8, 20. A global survey of the role of ultraviolet radiation and hormonal influences in the development of melasma. Our present research aims to study the clinicoepidemiological pattern and the precipitating or provocation factors in melasma. All female patients with a history of melasma were eligible for the study.
Confettilike sparing a diagnostic clinical feature of melasma. Overall, our findings indicate that it is an effective coadjuvant treatment for melasma in combination with topical 4% hydroquinone and sunscreen spf 50. Few studies show that melasma accounts for 4 10% of the new cases in the dermatology hospital, as a referral. Crosssectional study of psychiatric morbidity in patients. A total of 312 patients were enrolled for the study over a period of. Cosmetic contact sensitivity in patients with melasma. The youngest age in our study was 20 years and eldest was 68 years.
Melasma is a commonly acquired hypermelanosis of the skin characterised by browngrey patches predominately found on sunexposed areas of skin. So this study was conducted on 500 cases of melasma attending at skin opd. Confettilike sparing a diagnostic clinical feature of. A clinicoepidemiological study of facial melanosis iffat hassan, samia aleem, yasmeen jabeen bhat, parvaiz anwar department of dermatology, sexually transmitted diseases and leprosy, govt. This study was conducted to correlate the clinical, etiological and histopathological features of disease process.
An international journal of research in ayush and allied. Hormonal birth control methods are effective in preventing pregnancy, but can cause hyperpigmentation in some women. The melasma area and severity index masi is a common outcome measure that is validated as a tool to measure facial hyperpigmentation. Melasma is an acquired increased pigmentation of the skin, characterized by graybrown symmetrical patches, mostly in the sunexposed areas of the skin. Recent indian studies 21,22 report high prevalence of anxiety and depression as much as up to 84% of the patients in melasma. The pathogenesis is unknown, but genetic or hormonal influences with uv radiation are important. Although melasma is a benign condition, it can cause severe psychological distress, and social and emotional problems. The most predominant pattern was centrofacial and was observed in 3843 88. It is more common in women than in men and generally appears for the first time in the 20s to 50s, or during pregnancy.
Methods in this study, 23 participants with melasma applied a 2% ta formulation to the whole face for. A total of 312 patients were enrolled for the study over a period of one year. A clinicoepidemiological study of melasma in 402 patients in an. Hyperpigmentation while on birth control healthfully. A clinicoepidemiological study of 312 cases melasma is an acquired increased pigmentation of the skin. A clinico dermoscopic study of melasma in a tertiary care. Study site and population the study was conducted in the department of dermatology of a tertiary care center and teaching hospital. Although the prevalence of melasma has not been investigated in most countries, melasma accounts for about 410% of new cases in dermatology hospitals 3, 4. Melasma was most commonly observed in agriculturists 65%, p melasma for duration above 6 months. Histopathological comparison of lesional and perilesional.
A clinical, etiological and histopathological study of. Melasma is a common acquired disorder of hyperpigmentation that occurs usually in female individuals 90% of cases. A descriptive study published on mar 7, 2017 melasma is a third most commonly cited skin disorders was pigmentary problem diagnosed most often, other two are. It has now been correlated to the melasma severity score, a global score incorporating patient assessment of their. Melasma is common among women with darker complexion skin type ivvi. This study aimed to establish the epidemiological pattern of melasma in patients attending our hospital and to study the variation in demographics, etiological factors, and clinical features in melasma occurring in males and females. The major precipitating factor for melasma in our study. Hyperpigmentation, also called melasma, occurs when changing hormone levels cause patches of brown or grayish skin to appear on the face.
Total 25 patients presenting with acquired facial melanosis were included in the study. There are numerous modalities of treatment currently in use for this disease, of which the chemical peeling is very commonly used. A clinicoepidemiological study of 312 cases by achar and rathi, published in the julyaugust issue. The prevalence and correlates of haematological abnormalities in adult inpatients with.
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